課程名稱 |
核醣核酸生物學 Rna Biology |
開課學期 |
108-2 |
授課對象 |
生命科學院 生命科學所 |
授課教師 |
朱家瑩 |
課號 |
LS5049 |
課程識別碼 |
B21 U1700 |
班次 |
|
學分 |
2.0 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期四3,4(10:20~12:10) |
上課地點 |
生科4C |
備註 |
與朱雪萍合授 總人數上限:20人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1082LS5049_ |
課程簡介影片 |
|
核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
|
為確保您我的權利,請尊重智慧財產權及不得非法影印
|
課程概述 |
The role of RNA in regulating gene expression has become a topic of intense interest. This course will focus on current research in the RNA field. We will explore and discuss the knowledge and mechanism whereby RNA can regulate gene expression with examples in various model systems. The course will also highlight the application of this knowledge in therapeutics and research at the final section. |
課程目標 |
This course will provide a comprehensive interpretation that is intended for students who are interested in RNA biology, the regulation of gene expression, genetics, genomics or molecular biology. |
課程要求 |
Students are asked to actively participate in the discussion of research papers for each topic. Students are also asked to develop a consolidated version of research proposal during the class, with a stepwise writing of abstract, research rationales, specific aims and the final proposal. A final oral presentation for research proposal is also required for each student. Grading standard is based on the achievement of each assignment, and the oral presentation of research proposal. |
預期每週課後學習時數 |
|
Office Hours |
|
指定閱讀 |
|
參考書目 |
待補 |
評量方式 (僅供參考) |
|
週次 |
日期 |
單元主題 |
第1週 |
3/05 |
Organization/ Writing the Research Proposal (CYC) |
第2週 |
3/12 |
Introduction/ RNA synthesis (CYC) |
第3週 |
3/19 |
RNA splicing and processing (CYC) * (顏建平, 王柏峰, 胡夢純) |
第4週 |
3/26 |
RNA editing and modification (CYC) * 陳瑋廷、王煒辰、李原祚 |
第5週 |
4/02 |
Holiday |
第6週 |
4/09 |
RNA degradation (CYC) * (蘇苡嘉, 李淑芬, 解淮清) |
第7週 |
4/16 |
RNAi (I): eukaryotic RNAi (CYC) |
第8週 |
4/23 |
RNAi (II): prokaryotic RNAi (CYC) * (廖乙馨, 蔡如宣) |
第9週 |
4/30 |
Small non-coding RNA (I): miRNAs and translational control in animals (CYC) |
第10週 |
5/07 |
Small non-coding RNA (II): piRNAs and RNA-directed DNA methylation (CYC) * (駱辰嘉, 謝宥宏, 林万焜) |
第11週 |
5/14 |
Long non-coding RNAs (HPC) * (楊博丞, 楊仁龍, 侯冠竹) |
第12週 |
5/21 |
Natural antisense and circular RNAs (HPC) * (陳品縈, 劉律節, 林恆毅) |
第13週 |
5/28 |
Student Proposal Presentation (1) 劉律節、陳品縈、林恆毅、廖乙馨、李原祚 |
第14週 |
6/04 |
Student Proposal Presentation (2) 解淮清、王煒晨、李淑芬、胡夢純、林万焜 |
第15週 |
6/11 |
Student Proposal Presentation (3) 謝宥宏、顏建平、楊仁能、駱辰嘉、陳瑋廷 |
第16週 |
6/18 |
Student Proposal Presentation (4) 王柏峰、蔡如宣、蘇苡嘉、楊博丞、侯冠竹 |
第17週 |
6/28 |
Holiday |
第18週 |
7/2 |
Course wrap-up |
|